Publications

2018

Pongrakhananon, V., Saito, H., Hiver, S., Abe, T., Shioi, G., Meng, W. and Takeichi, M (2018) CAMSAP3 maintains neuronal polarity through regulation of microtubule stability. Proc Natl Acad Sci U S A 115, 9750-9755.

Essay

Takeichi, M. (2018). Historical review of the discovery of cadherin, in memory of Tokindo Okada. Dev Growth Differ 60, 3-13.

Review

Takeichi, M. (2018). Multiple functions of alpha-catenin beyond cell adhesion regulation. Curr Opin Cell Biol 54, 24-29.

2017

Ito, S., Okuda, S., Abe, M., Fujimoto, M., Onuki, T., Nishimura, T., and Takeichi, M. (2017). Induced cortical tension restores functional junctions in adhesion-defective carcinoma cells. Nat Commun 8, 1834.

Vassilev, V., Platek, A., Hiver, S., Enomoto, H., and Takeichi, M. (2017). Catenins Steer Cell Migration via Stabilization of Front-Rear Polarity. Dev Cell 43, 463-479 e465.

Hayashi, S., Inoue, Y., Hattori, S., Kaneko, M., Shioi, G., Miyakawa, T., and Takeichi, M. (2017). Loss of X-linked Protocadherin-19 differentially affects the behavior of heterozygous female and hemizygous male mice. Sci Rep 7, 5801.

2016

Nishimura, T., Ito, S., Saito, H., Hiver, S., Shigetomi, K., Ikenouchi, J., and Takeichi, M. (2016). DAAM1 stabilizes epithelial junctions by restraining WAVE complex-dependent lateral membrane motility. J Cell Biol 215, 559-573.

Toya, M., Kobayashi, S., Kawasaki, M., Shioi, G., Kaneko, M., Ishiuchi, T., Misaki, K., Meng, W., and Takeichi, M. (2016). CAMSAP3 orients the apical-to-basal polarity of microtubule arrays in epithelial cells. Proc Natl Acad Sci U S A 113, 332-337.

Review

Toya, M., and Takeichi, M. (2016). Organization of non-centrosomal microtubules in epithelial cells. Cell Struct Funct.

2015

Popov, L.M., Marceau, C.D., Starkl, P.M., Lumb, J.H., Shah, J., Guerrera, D., Cooper, R.L., Merakou, C., Bouley, D.M., Meng, W., et al. (2015). The adherens junctions control susceptibility to Staphylococcus aureus alpha-toxin. Proc Natl Acad Sci U S A 112, 14337-14342.

Review

Hayashi, S., and Takeichi, M. (2015). Emerging roles of protocadherins: from self-avoidance to enhancement of motility. J Cell Sci 128, 1455-1464.

西村珠子、竹市雅俊 「折れ曲がる－ニワトリの神経管形成を例に」 実験医学, 33 (3): 399-404 (2015)

2014

Tsukasaki, Y., Miyazaki, N., Matsumoto, A., Nagae, S., Yonemura, S., Tanoue, T., Iwasaki, K., and Takeichi, M. (2014). Giant cadherins Fat and Dachsous self-bend to organize properly spaced intercellular junctions. Proc Natl Acad Sci U S A 111, 16011-16016.

Sako-Kubota, K., Tanaka, N., Nagae, S., Meng, W., and Takeichi, M. (2014). Minus end-directed motor KIFC3 suppresses E-cadherin degradation by recruiting USP47 to adherens junctions. Mol Biol Cell.

Hayashi, S., Inoue, Y., Kiyonari, H., Abe, T., Misaki, K., Moriguchi, H., Tanaka, Y., and Takeichi, M. (2014). Protocadherin-17 Mediates Collective Axon Extension by Recruiting Actin Regulator Complexes to Interaxonal Contacts. Dev Cell.

Review

Takeichi, M. (2014). Dynamic contacts: rearranging adherens junctions to drive epithelial remodelling. Nat Rev Mol Cell Biol.

Nishimura, T. (2014). Making the neural plate to fold into a tube. New Principles in Developmental Processes.

2013

Nagae, S., Meng, W., and Takeichi, M. (2013). Non-centrosomal microtubules regulate F-actin organization through the suppression of GEF-H1 activity. Genes Cells.

2012

Tanaka, N., Meng, W., Nagae, S., and Takeichi, M. (2012). Nezha/CAMSAP3 and CAMSAP2 cooperate in epithelial-specific organization of noncentrosomal microtubules. Proc Natl Acad Sci U S A 109, 20029-20034.

Vassilev, V.S., Mandai, M., Yonemura, S., and Takeichi, M. (2012). Loss of N-cadherin from the endothelium causes stromal edema and epithelial dysgenesis in the mouse cornea. Invest Ophthalmol Vis Sci 53, 7183-7193.

Nishimura, T., Honda, H., and Takeichi, M. (2012). Planar cell polarity links axes of spatial dynamics in neural-tube closure. Cell 149, 1084-1097.

Ishiuchi, T., and Takeichi, M. (2012). Nectins localize Willin to cell-cell junctions. Genes Cells 17, 387-397.

Review

Hirano, S., and Takeichi, M. (2012). Cadherins in brain morphogenesis and wiring. Physiol Rev 92, 597-634.

2011

Ishiuchi, T., and Takeichi, M. (2011). Willin and Par3 cooperatively regulate epithelial apical constriction through aPKC-mediated ROCK phosphorylation. Nat Cell Biol 13, 860-866.

Taguchi, K., Ishiuchi, T., and Takeichi, M. (2011). Mechanosensitive EPLIN-dependent remodeling of adherens junctions regulates epithelial reshaping. J Cell Biol 194, 643-656.

Togashi, H., Kominami, K., Waseda, M., Komura, H., Miyoshi, J., Takeichi, M., and Takai, Y. (2011). Nectins Establish a Checkerboard-like Cellular Pattern in the Auditory Epithelium. Science 333, 1144-1147.

Review

Oda, H., and Takeichi, M.(2011). Evolution: structural and functional diversity of cadherin at the adherens junction. J Cell Biol 193, 1137-1146.

Takeichi, M. (2011). Self-organization of animal tissues: cadherin-mediated processes. Dev Cell 21, 24-26.

2010

Essay

Takeichi, M. (2010). Accidental encounters: the chance to solve a mystery. Nat Cell Biol 12, 2.

2009

Ito, S., and Takeichi, M. (2009). Dendrites of cerebellar granule cells correctly recognize their target axons for synaptogenesis in vitro. Proc Natl Acad Sci U S A 106, 12782-12787.

Ishiuchi, T., Misaki, K., Yonemura, S., Takeichi, M., and Tanoue, T. (2009). Mammalian Fat and Dachsous cadherins regulate apical membrane organization in the embryonic cerebral cortex. J Cell Biol 185, 959-967

Review

Nishimura, T., and Takeichi, M. (2009). Remodeling of the adherens junctions during morphogenesis. Curr Top Dev Biol 89, 33-54.

Meng, W., and Takeichi, M. (2009). Adherens junction: molecular architecture and regulation. Cold Spring Harb Perspect Biol 1, a002899.

2008

Meng, W., Mushika, Y., Ichii, T., and Takeichi, M. (2008). Anchorage of microtubule minus ends to adherens junctions regulates epithelial cell-cell contacts. Cell 135, 948-959.

Nakao, S., Platek, A., Hirano, S., and Takeichi, M. (2008). Contact-dependent promotion of cell migration by the OL-protocadherin-Nap1 interaction. J Cell Biol 182, 395-410.

Abe, K., andTakeichi, M. (2008) EPLIN mediates linkage of the cadherin-catenin complex to F-actin and stabilizes the circumferential actin belt. Proc. Natl. Acad. Sci. USA, 105, 13-19.

Nishimura , T., and Takeichi, M. (2008) Shroom3-mediated recruitment of Rho kinases to the apical cell junctions regulates epithelial and neuroepithelial planar remodeling. Development 135, 1493-1502.

Review

Suzuki, S. C., and Takeichi, M. (2008). Cadherins in neuronal morphogenesis and function. Dev Growth Differ 50 Suppl 1, S119-130.

2007

Kametani, Y., and Takeichi, M. (2007) Basal-to-apical cadherin flow at cell junctions. Nature Cell Biol., 9, 92-98.

Kadowaki, M., Nakamura, S., Machon, O., Krauss, S., Radice, G.L., and Takeichi M. (2007). N-cadherin mediates cortical organization in the mouse brain. Develop. Biol., 304, 22-33.

Hoshino, H., Uchida, T., Otsuki T., Kawamoto, S., Okubo, K., Takeichi, M., and Chisaka, O. (2007) Cornichon-like Protein (CNIL) Facilitates Secretion of HB-EGF and Regulates Proper Development of Cranial Nerves. Mol Biol Cell. 18,1143-1152.

Abe, K., and Takeichi, M. (2007) NMDA Receptor activation induces calpain-mediated beta-catenin cleavages for triggering gene expression. Neuron 53, 387-397.

Lee, D.M., Kiener, H.P., Agarwal, S.K., Noss, E.H., Watts, G.F., Chisaka, O., Takeichi, M., and Brenner, M.B. (2007) Cadherin-11 in synovial lining formation and pathology in arthritis. Science 315, 1006-1010.

Suzuki, S.C., Furue, H., Koga, K., Jiang, N., Nohmi M., Shimazaki, Y., Katoh-Fukui, Y., Yokoyama, M., Yoshimura, M., and Takeichi, M. (2007) Cadherin-8 is required for the first relay synapses to receive functional inputs from primary sensory afferents for cold sensation.J. Neurosci. 27, 3466-76.

Ichii, T., and Takeichi, M. (2007) p120-catenin regulates microtubule dynamics and cell migration in a cadherin-independent manner. Genes to Cells 12, 827-839.

Sone, M., Hayashi, T., Tarui, H., Agata, K., Takeichi, M., and Nakagawa, S. (2007). The mRNA-like noncoding RNA Gomafu constitutes a novel nuclear domain in a subset of neurons. J Cell Sci 120, 2498-2506.

Uemura, M., Nakao, S., Suzuki, S.T., Takeichi, M., and Hirano, S. (2007) OL-protocadherin is essential for growth of striatal axons and thalamocortical projections. Nature Neuroscience, 10, 1151-1159.

2006

Togashi, H., Miyoshi, J., Honda, T., Sakisaka, T., Takai, T., and Takeichi, M. (2006) Interneurite affinity is regulated by heterophilic nectin interactions in concert with the cadherin machinery. J. Cell Biol., 174, 141-151.

Uemura, M., and Takeichi, M. (2006) alpha N-catenin deficiency causes defects in axon migration and nuclear organization in restricted regions of the mouse brain. Dev. Dynamics 235, 2559-2566.

Otani,T., Ichii, T., Aono, S., and Takeichi, M. (2006) Cdc42 GEF Tuba regulates the junctional configuration of simple epithelial cells. J. Cell Biol., 175, 135-146.

Tanabe, K., Takahashi,Y., Sato, Y., Kawakami, K., Takeichi, M., and Nakagawa, S. (2006) Cadherin is required for dendritic morphogenesis and synaptic terminal organization of retinal horizontal cells. Development 133, 4085-4096.

Nagae, S., Tanoue, T., and Takeichi, M. (2006) Temporal and spatial expression profiles of the Fat3 protein, a giant cadherin molecule, during mouse development. Develop. Dynamics 236, 534-543.

Review

Takeichi, M. (2006) The cadherin superfamily in neuronal recognitions and interactions. Nature Reviews Neurosciences, 8, 11-20.

2005

Nakao, S., Uemura, M., Aoki, E., Suzuki, S.T., Takeichi, M., and Hirano, S. (2005) Distribution of OL-protocadherin in axon fibers in the developing chick nervous system. Brain Res. Mol. Brain Res. 134, 294-308.

Kubo, F., Takeichi, M., and Nakagawa, S. (2005) Wnt2b inhibits differentiation of retinal progenitor cells in the absence of Notch activity by downregulating the expression of proneural genes. Development 132, 2759-2770.

Review

Takeichi, M., and Abe, K. (2005) Synaptic contact dynamics controlled by cadherin and catenins. Trends in Cell Biol., 15, 216-221.

Tanoue, T., and Takeichi, M. (2005) New insights into Fat cadherins. J. Cell Sci., 118, 2347-2353.

2004

Tanoue, T., and Takeichi, M. (2004). Mammalian Fat1 cadherin regulates actin dynamics and cell-cell contact. J Cell Biol 165, 517-528.

Shima, Y., Kengaku, M., Hirano, T., Takeichi, M., and Uemura, T. (2004). Regulation of dendritic maintenance and growth by a mammalian 7-pass transmembrane cadherin. Dev Cell 7, 205-216.

Abe, K., Chisaka, O., Van Roy, F., and Takeichi, M. (2004). Stability of dendritic spines and synaptic contacts is controlled by alpha N-catenin. Nat Neurosci 7, 357-363.

Tanabe, K., Takeichi, M., and Nakagawa, S. (2004). Identification of a nonchordate-type classic cadherin in vertebrates: chicken Hz-cadherin is expressed in horizontal cells of the neural retina and contains a nonchordate-specific domain complex. Dev Dyn 229, 899-906.

2003

Kubo, F., Takeichi, M., and Nakagawa, S. (2003) Wnt2b controls retinal cell differentiation at the ciliary marginal zone. Development 130,587-598.

Nakagawa, S., Takada, S., Takada, R., and Takeichi, M. (2003). Identification of the laminar-inducing factor: Wnt-signal from the anterior rim induces correct laminar formation of the neural retina in vitro. Dev Biol 260, 414-425.

2002

Iwai, Y., Hirota, Y., Ozaki, K., Okano, H., Takeichi, M., and Uemura, T. (2002) DN-Cadherin is required for spatial arrangement of axon terminals and their targets, and ultrastructural organization of synapses in the Drosophila visual system. Mol. Cell. Neuroscience 19, 375-388.

Niwa, R., Nagata-Ohashi, K., Takeichi, M., Mizuno, K., and Uemura, T. (2002) Control of actin reorganization by Slingshot, a family of phosphatases that dephosphorylate ADF/cofilin. Cell 108, 233-246.

Shima, Y., Copeland, N.G., Gilbert, D.J., Jenkins, N.A., Chisaka, O., Takeichi, M., and Uemura, T. (2002) Differential expression of the seven-pass transmembrane cadherin genes Celsr1-3 and distribution of the Celsr2 protein during mouse development. Dev. Dyn. 223, 321-323.

Umemiya, T., Takasu, E., Takeichi, M., Aigaki, T., and Nose, A. (2002) Forked end: a novel transmembrane protein involved in neuromuscular specificity in Drosophila identified by gain-of-function screening. J. Neurobiol. 51, 205-214.

Peng, Y.F., Mandai, K., Nakanishi, H., Ikeda, W., Asada, M., Momose, Y., Shibamoto, S., Yanagihara, K., Shiozaki, H., Monden, M., Takeichi, M., and Takai. Y. (2002) Restoration of E-cadherin-based cell-cell adhesion by overexpression of nectin in HSC-39 cells, a human signet ring cell gastric cancer cell line. Oncogene 21, 4108-4119.

Togashi, H., Abe, K., Mizoguchi, A., Chisaka, O., and Takeichi, M. (2002) Cadherin regulates dendritic spine morphogenesis. Neuron 35, 77-89.

2001

Inoue, T., Tanaka, T., Takeichi, M., Chisaka, O., Nakamura, S., and Osumi, N. (2001) Role of cadherins in maintaining the compartment boundary between the cortex and striatum during development. Development 128, 561-569.

Shimada, Y., Usui, T., Yanagawa, S., Takeichi, M., and Uemura, T. (2001) Asymmetric colocalization of Flamingo, a seven-pass transmembrane cadherin, and Dishevelled in planar cell polarization. Current Biology 11, 859-863.

Watari, N., Kameda, Y., Takeichi, M., and Chisaka, O. (2001) Hoxa3 regulates integration of glossopharyngeal nerve precursor cells. Develop. Biol. 240, 15-31.

Horikawa, K., and Takeichi, M. (2001) Requirement of juxtamembrane domain of the cadherin cytoplasmic tail for morphogenetic cell rearrangement during myotome development. J. Cell Biol. 155, 1297-1306.

Kataoka, Y., Takeichi, M., and Uemura, T. (2001) Developmental roles and molecular characterization of a Drosophila homologue of Arabidopsis Argonaute1, the founder of a novel gene superfamily. Genes to Cells 6, 313-25.

2000

Manabe, M., Togashi, H., Uchida, N., Suzuki, S.C., Hayakawa, Y., Yamamoto, M., Yoda, H., Miyakawa, T., Takeichi, M., and Chisaka, O. (2000) Loss of cadherin-11 adhesion receptor enhances plastic changes in hippocampal synapses and modifies behavioral responses. Mol. Cell. Neuroscience, 15, 534-546.

Honjo, Y., Nakagawa, S., and Takeichi, M. (2000) Blockade of cadherin-6B activity perturbs the distribution of PSD-95 family proteins in retinal neurons. Genes to Cells 5, 309-318.

Review

Yagi, T. and Takeichi, M. (2000) Cadherin superfamily genes: functions, genomic organization, and neurologic diversity. Genes & Dev. 14, 1169-1180.

1999

Aono, S., Nakagawa, S., Reynolds, A.B., and Takeichi, M. (1999) p120ctn acts as an inhibitory regulator of cadherin function in colon carcinoma cells. J. Cell Biol., 145, 551-562.

Usui, T., Shima, Y., Shimada, Y., Hirano, S., Burgess, R.W., Schwarz, T.L., Takeichi, M., and Uemura, T. (1999) Flamingo, a seven-pass transmembrane cadherin, regulates planar cell polarity under the control of Frizzled. Cell 98, 585-595.

1998

Shishido, E., Takeichi, M., and Nose, A. (1998) Drosophila synapse formation: Regulation by transmembrane protein with Leu-rich repeats, Capricous. Science 280, 2118-2121.

Nakagawa, S., and Takeichi, M. (1998) Neural crest emigration from the neural tube depends on regulated cadherin expression. Development 125, 2963-2971.

Watabe-Uchida, M., Uchida, N., Imamura, Y., Nagafuchi, A., Fujimoto, K., Uemura, T., Vermeulen, S., van Roy, F., Adamson, E.D., and Takeichi, M. (1998) alpha-Catenin-vinculin interaction functions to organize the apical junctional complex in epithelial cells. J. Cell Biol. 142, 847-857.

1997

Radice, G.L., Rayburn, H., Matsunami, H., Knudsen, K.A., Takeichi, M. and Hynes, R.O. (1997) Developmental defects in mouse embryos lacking N-cadherin. Develop. Biol., 181, 64-78.

Iwai, Y., Usui, T., Hirano, S., Steward, R., Takeichi, M. and Uemura. T. (1997) Axon patterning requires DN-cadherin, a novel neuronal adhesion receptor, in the Drosophila embryonic CNS. Neuron 19, 77-89.

Suzuki, S.C., Inoue, T., Kimura, Y., Tanaka, T. and Takeichi, M. (1997) Neuronal circuits are subdivided by differential expression of type-II classic cadherins in postnatal mouse brains. Mol. Cell. Neuroscience 9, 433-447.

Radice, G.L., Ferreira-Cornwell, M.C., Robinson, S.D., Rayburn, H., Chodosh, L.A., Takeichi, M. and Hynes, R.O. (1997) Precocious mammary gland development in P-cadherin-deficient mice. J. Cell Biol. 17, 1025-1032.

1996

Uemura, T., Oda, H., Kraut, R., Hayashi, S., Kataoka, Y. and Takeichi, T. (1996) Zygotic DE-cadherin expression is required for processes of dynamic epithelial cell rearrangement in the Drosophila embryo. Genes & Develop. 10, 659-671.

Uchida, N., Honjo, Y., Johnson, K.R., Wheelock, M.J. and Takeichi, M. (1996) The catenin/cadherin adhesion system is localized in synaptic junctions, bordering the active zone. J. Cell Biol. 135, 767-779.

1995

Overduin, M., Harvey, T.S., Bagby, S., Tong, K.I., Yau, P., Takeichi, M. and Ikura, M. (1995) Solution structure of the epithelial cadherin domain responsible for selective cell adhesion. Science 267, 386-389.

Nakagawa, S. and Takeichi, M. (1995) Neural crest cell-cell adhesion controlled by sequential and subpopulation-specific expression of novel cadherins. Development 121, 1321-1332.

Matsunami, H. and Takeichi, M. (1995) Fetal brain subdivisions defined by R- and E-cadherin expressions: evidence for the role of cadherin activity in region-specific, cell-cell adhesion. Develop. Biol. 172, 466-478.

Review

Takeichi, M. (1995) Morphogenetic roles of classic cadherins. Current Opinion in Cell Biol. 7, 619-627.

1994

Shimamura, K., Hirano, S., McMahon, A.P. and Takeichi, M. (1994) Wnt-1-dependent regulation of local E-cadherin and aN-catenin expression in the embryonic mouse brain. Development 120, 2225-2234.

Watabe, M., Nagafuchi, A., Tsukita, S., and Takeichi, M. (1994) Induction of polarized cell-cell association and retardation of growth by activation of the E-cadherin-catenin adhesion system in a dispersed carcinoma line. J. Cell Biol., 127, 247-256.

Oda, H., Uemura, T., Harada, Y., Iwai, Y. and Takeichi, M. (1994) A Drosophila homolog of cadherin associated with Armadillo and essential for embryonic cell-cell adhesion. Develop. Biol., 165, 716-726.

1993

Fujimori, T. and Takeichi, M. (1993) Disruption of epithelial cell-cell adhesion by exogenous expression of a mutated non-functional N-cadherin. Mol. Biol. Cell 4, 37-47.

Oda, H., Uemura, T., Shiomi, K., Nagafuchi, A., Tsukita, S. and Takeichi, M. (1993) Identification of a Drosophila homologue of a-catenin and its association with the armadillo protein. J. Cell Biol. 121,1133-1140.

Steinberg, M.S. and Takeichi, M. (1993) Experimental specification of cell sorting, tissue spreading and specific patterning by quantitative differences in cadherin expression. Proc. Natl Acad. Sci. USA 91, 206-209.

Review

Takeichi, M. (1993) Cadherins in cancer: Implication for invasion and metastasis. Curr. Opinion Cell Biol. 5, 806-811.

1992

Hirai. Y., Takebe, K., Takahashi, M., Kobayashi, S. and Takeichi, M. (1992) Epimorphin: A mesenchymal protein essential for epithelial morphogenesis. Cell 69, 471-481.

Shimamura, K., Takahashi, T. and Takeichi, M. (1992) E-cadherin expression in a particular subset of sensory neurons. Dev. Biol. 152, 242-254.

Matsuyoshi, N., Hamaguchi, M., Taniguchi, S., Nagafuchi, A., Tsukita, S. and Takeichi, M. (1992) Cadherin-mediated cell-cell adhesion is perturbed by v-src tyrosine phosphorylation in metastatic fibroblasts. J. Cell Biol. 118, 703-714.

Hirano, S., Kimoto, N., Shimoyama, Y., Hirohashi, S. and Takeichi, M. (1992) Identification of a neural a-catenin as a key regulator of cadherin function and multicellular organization. Cell 70, 293-301.

Redies, C., Inuzuka, H. and Takeichi, M. (1992) Restricted expression of N- and R-cadherin on neurites of the developing chicken CNS. J. Neuroscience 12, 3525-3534.

Shimamura, K. and Takeichi, M. (1992) Local and transient expression of E-cadherin involved in mouse embryonic brain morphogenesis. Development 116, 1011-1019.

1991

Inuzuka, H., Miyatani, S. and Takeichi, M. (1991) R-cadherin: A novel Ca2+-dependent cell-cell adhesion molecule expressed in the retina. Neuron 7, 69-79.

Nagafuchi, A., Takeichi, M. and Tsukita, S. (1991) The 102kd cadherin-associated protein: Similarity to vinculin and posttranscriptional regulation of expression. Cell 65, 849-857.

Review

Takeichi, M. (1991) Cadherin cell adhesion receptors as a morphogenetic regulator. Science 251, 1451-1455.

1990

Nose, A., Tsuji, K. and Takeichi, M. (1990) Localization of specificity determining sites in cadherin adhesion molecules. Cell 61, 147-155.

Fujimori, T., Miyatani, S. and Takeichi, M. (1990) Ectopic expression of N-cadherin perturbs histogenesis in Xenopus embryos. Development 110, 97-104.

Review

Takeichi, M. (1990) Cadherins: A molecular family important in selective cell-cell adhesion. Annu. Rev. Biochem. 59, 237-252.

1989

Hirai, Y., Nose, A., Kobayashi, S. and Takeichi, M. (1989) Expression and role of E- and P-cadherin adhesion molecules in embryonic histogenesis. I. Lung epithelial morphogenesis. Development 105 , 263-270.

Hashimoto, M., Niwa, O., Nitta, Y., Takeichi, M. and Yokoro, K., (1989) Unstable expression of E-cadherin adhesion molecules in metastatic ovarian tumor cells. Jpn. J. Cancer Res. 80, 459-463.

Miyatani, S., Shimamura, K., Hatta, M., Nagafuchi, A., Nose, A., Matsunaga, M., Hatta, K. and Takeichi, M. (1989) Neural cadherin: Role in selective cell-cell adhesion. Science 245, 631-635.

Nagafuchi, A. and Takeichi, M. (1989) Transmembrane control of cadherin-mediated cell adhesion: A 94kd protein functionally associated with a specific region of the cytoplasmic domain of E-cadherin. Cell Regulation 1, 37-44.

1988

Hatta, K., Nose, A., Nagafuchi, A. and Takeichi, M. (1988) Cloning and expression of cDNA encoding a neural calcium-dependent cell adhesion molecule: Its identity in the cadherin gene family. J. Cell Biol. 106, 873-881.

Matsunaga, M., Hatta, K. and Takeichi, M. (1988) Role of N-cadherin cell adhesion molecules in the histogenesis of neural retina. Neuron 1, 289-295.

Matsunaga, M., Hatta, K. and Takeichi, M. (1988) Guidance of retinal nerve fibers by N-cadherin adhesion molecules. Nature 334, 62-64.

Nose, A., Nagafuchi, A. and Takeichi, M. (1988) Expressed recombinant cadherins mediate cell sorting in model systems. Cell 54, 993-1001.

Nagafuchi, A. and Takeichi, M. (1988) Cell binding function of E-cadherin is regulated by the cytoplasmic domain. EMBO J. 7, 3679-3684.

Review

Takeichi, M. (1988) The cadherins: Cell-cell adhesion molecules controlling animal morphogenesis. Development 102, 639-655.

1987

Hatta, K., Takagi, S., Fujisawa, H. and Takeichi, M. (1987) Spatial and temporal expression pattern of N-cadherin cell adhesion molecules correlated with morphogenetic processes of chicken embryos. Develop. Biol. 120, 215-227.

Nagafuchi, A., Shirayoshi, Y., Okazaki, K., Yasuda, K. and Takeichi, M. (1987) Transformation of cell adhesion properties by exogenously introduced E-cadherin cDNA. Nature 329, 341-343.

Nose, A., Nagafuchi, A. and Takeichi, M. (1987) Isolation of placental cadherin cDNA: Identification of a novel gene family for cell-cell adhesion molecules. EMBO J. 6, 3655-3661.

Hirano, S., Nose, A., Hatta, K., Kawakami, A. and Takeichi, M. (1987) Calcium-dependent cell-cell adhesion molecules (cadherins): Subclass-specificities and possible involvement of actin bundles. J. Cell Biol. 105, 2501-2510.

Review

Takeichi, M. (1987) Cadherins: A molecular family essential for selective cell-cell adhesion and animal morphogenesis. Trends in Genetics 3, 213-217.

1986

Hatta, K. and Takeichi, M. (1986) Expression of N-cadherin adhesion molecules associated with early morphogenetic events in chicken embryos. Nature 320, 447-449.

Shirayoshi, Y., Hatta, K., Hosoda, M., Tsunasawa, S., Sakiyama, F. and Takeichi, M. (1986) Cadherin cell adhesion molecules with distinct binding specificities share a common structure. EMBO J. 5, 2485-2488.

Nose, A. and Takeichi, M. (1986) A novel cadherin adhesion molecule: Its expression patterns associated with implantation and organogenesis of mouse embryos. J. Cell Biol. 103, 2649-2658.

1985

Hatta, K., Okada, T.S. and Takeichi, M. (1985) A monoclonal antibody inhibiting the Ca2+-dependent cell-cell adhesion of brain cells: Possible role of its target antigen in animal pattern formation. Proc. Nat. Acad. Sci. USA 82, 2789-2793.

1984

Yoshida-Noro, C., Suzuki, N. and Takeichi, M. (1984) Molecular nature of the calcium-dependent cell-cell adhesion system in mouse teratocarcinoma and embryonic cells studied with a monoclonal antibody. Develop. Biol. 101, 19-27.

1983

Shirayoshi, Y., Okada, T.S. and Takeichi, M. (1983) The calcium-dependent cell-cell adhesion system regulates inner cell mass formation and cell surface polarization in early mouse development. Cell 35, 631-638.

1982

Yoshida, C. and Takeichi, M. (1982) Teratocarcinoma cell adhesion: Identification of a cell surface protein involved in calcium-dependent cell aggregation. Cell 28, 217-224.

1981

Takeichi, M., Atsumi, T., Yoshida, C., Uno, K. and Okada, T.S. (1981) Selective adhesion of embryonal carcinoma cells and differentiated cells by Ca2+-dependent sites. Develop. Biol. 87, 340-350.

1980

Urushihara, H. and Takeichi, M. (1980) Identification of a glycoprotein relevant to Ca2+-independent aggregation of Chinese hamster fibroblasts. Cell 20, 363-371.

1979

Urushihara, H., Ozaki, H.S. and Takeichi, M. (1979) Immunological detection of cell surface components related with aggregation of Chinese hamster and chick embryonic cells. Develop. Biol. 70, 206-216.

Takeichi, M., Ozaki, H.S., Tokunaga, K. and Okada, T.S. (1979) Experimental manipulation of cell surface to affect cellular recognition mechanisms. Develop. Biol. 70, 195-205.

1977

Takeichi, M. (1977) Functional correlation between cell adhesive properties and some cell surface proteins. J. Cell Biol. 75, 464-474.